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CODE: SYJZDNPPC
  • This two-piece kit includes both Night Treatment and Day Crème, giving you around the clock moisturizing treatment to help repair and reduce visible signs of aging.

    Night Treatment: aloe vera leaf juice, sunflower seed oil, palmitoyl Hexapeptide-12, shea butter, candelilla/jojoba/rice bran polyglyceryl-3 esters, palmitoyl tripeptide-37, caprooyl tetrapeptide-3, apple fruit cell culture extract, rose hip seed oil, caprylic/capric triglyceride, kukui seed oil, swertia chirata extract, macadamia seed oil, glycerin, coconut oil, glyceryl stearate, neem oil, xylitylglucoside, anhydroxylitol, xylitol, sodium stearoyl lactylate, safflower oleosomes, cetearyl alcohol, hyaluronic acid, red algae extract, pomegranate fruit extract, maltodextrin, chamomile flower extract, calendula flower extract, green tea leaf extract, ceramide ng, gotu kola extract, arnica flower extract, pichia/resveratrol ferment extract, bamboo extract, pea extract, glucosamine HCl, willow bark extract, hydrolyzed algin, chlorella vulgaris extract, bakuchiol extract, sea water, phytosteryl isostearate, phospholipids, biosaccharide gum-1, lecithin, alpha glucan oligosaccharide, tocopherol acetate, retinyl palmitate, ascorbic acid, tetrahexyldecyl ascorbate, niacinamide, pantothenic acid, pyridoxine, cholecalciferol, thioctic acid, citric acid, glyceryl caprylate, glyceryl undecylenate, ubiquinone, dimethylaminoethanol, natural fragrance, xanthan gum, sodium phytate. Day Creme: aloe vera leaf juice, sunflower seed oil, caprylic/capric triglyceride, kukui seed oil, macadamia seed oil, cetearyl olivate, sorbitan olivate, shea butter, safflower oleosomes, hydrogenated olive oil, olive fruit oil, olive oil unsaponifiables, neem oil, glycerin, palmitoyl tripeptide-37, caprooyl tetrapeptide-3, myristlyl myristate, rose hip seed oil, phytosteryl isostearate, cetearyl alcohol, grape fruit cell extract, pomegranate fruit extract, red algae extract, xylitylglucoside, anhydroxylitol, xylitol, chamomile flower extract, calendula flower extract, gotu kola extract, arnica flower extract, ceramide ng, swertia chirata extract, phospholipids, green tea leaf extract, hyaluronic acid, biosaccharide gum-1, alpha-glucan oligosaccharide, oat kernel extract, hydrolyzed algin, chlorella vulgaris extract, sea water, tocopherol acetate, lecithin, retinyl palmitate, ascorbic acid, tetrahexyldecyl ascorbate, niacinamide, pantothenic acid, isomalt, pyridoxine, cholecalciferol, thioctic acid, glyceryl caprylate, glyceryl undecylenate, ubiquinone, dimethylaminoethanol, natural fragrance, sodium phytate, xanthan gum.

  • Choose Your Collection

    3 Kits - $270
    2 Kits - $198
    1 Kit - $118
  • Regular Price: $128

    $118

    Free Shipping

    Add To Bag

    (This is a one time payment)

Every purchase protected by our 100% Satisfaction Guarantee. If you are unsatisfied for any reason, return it within 90 days for a full refund. You only pay return shipping.


Night Treatment

This silky smooth cream contains Apple Stem Cell technology, Rice bran, Candelilla, Jojoba and 35 more ingredients to add natu-ral moisture and counteract age-causing dehydration. Wake up inthe morning to energized, fresher looking skin.


Ingredients: aloe vera leaf juice, sunflower seed oil, palmitoyl Hexapeptide-12, shea butter, candelilla/jojoba/rice bran polyglyceryl-3 esters, palmitoyl tripeptide-37, caprooyl tetrapeptide-3, apple fruit cell culture extract, rose hip seed oil, caprylic/capric triglyceride, kukui seed oil, swertia chirata extract, macadamia seed oil, glycerin, coconut oil, glyceryl stearate, neem oil, xylitylglucoside, anhydroxylitol, xylitol, sodium stearoyl lactylate, safflower oleosomes, cetearyl alcohol, hyaluronic acid, red algae extract, pomegranate fruit extract, maltodextrin, chamomile flower extract, calendula flower extract, green tea leaf extract, ceramide ng, gotu kola extract, arnica flower extract, pichia/resveratrol ferment extract, bamboo extract, pea extract, glucosamine HCl, willow bark extract, hydrolyzed algin, chlorella vulgaris extract, bakuchiol extract, sea water, phytosteryl isostearate, phospholipids, biosaccharide gum-1, lecithin, alpha glucan oligosaccharide, tocopherol acetate, retinyl palmitate, ascorbic acid, tetrahexyldecyl ascorbate, niacinamide, pantothenic acid, pyridoxine, cholecalciferol, thioctic acid, citric acid, glyceryl caprylate, glyceryl undecylenate, ubiquinone, dimethylaminoethanol, natural fragrance, xanthan gum, sodium phytate.

 

 

Day Crème

This rich, shiny-smooth formula absorbs deeply to help repair andreduce visible signs of aging. Gentle Olive Oil Emulsifiers and Grape Stem Cell technology help smooth skin and deliver the kind of suppleness that really helps you look young.


Ingredients: aloe vera leaf juice, sunflower seed oil, caprylic/capric triglyceride, kukui seed oil, macadamia seed oil, cetearyl olivate, sorbitan olivate, shea butter, safflower oleosomes, hydrogenated olive oil, olive fruit oil, olive oil unsaponifiables, neem oil, glycerin, palmitoyl tripeptide-37, caprooyl tetrapeptide-3, myristlyl myristate, rose hip seed oil, phytosteryl isostearate, cetearyl alcohol, grape fruit cell extract, pomegranate fruit extract, red algae extract, xylitylglucoside, anhydroxylitol, xylitol, chamomile flower extract, calendula flower extract, gotu kola extract, arnica flower extract, ceramide ng, swertia chirata extract, phospholipids, green tea leaf extract, hyaluronic acid, biosaccharide gum-1, alpha-glucan oligosaccharide, oat kernel extract, hydrolyzed algin, chlorella vulgaris extract, sea water, tocopherol acetate, lecithin, retinyl palmitate, ascorbic acid, tetrahexyldecyl ascorbate, niacinamide, pantothenic acid, isomalt, pyridoxine, cholecalciferol, thioctic acid, glyceryl caprylate, glyceryl undecylenate, ubiquinone, dimethylaminoethanol, natural fragrance, sodium phytate, xanthan gum.


CODE: SYJZDNPPC
  • *Results May Vary


  • Choose Your Collection

    3 Kits - $270
    2 Kits - $198
    1 Kit - $118
  • Regular Price: $128

    $118

    Free Shipping

    Add To Bag

    (This is a one time payment)

Every purchase protected by our 100% Satisfaction Guarantee. If you are unsatisfied for any reason, return it within 90 days for a full refund. You only pay return shipping.


Customer Reviews

858 Reviews   |   4.3 Average Rating   |   85% Recommend This Product 

Yes, the combo is recommended! *
By K.Joyce M. (Council Bluffs, IA) - 9/18/2025
After just three days of using the day creme, I was excited to notice a remarkable improvement in skin smoothness, skin tone, and lessening of lines. Knowing that the product is all natural sealed the deal. At age 90, I'm committed to nourishing my skin day and night.
  I Recommend This Product
  Verified Customer
Wonderful products *
By Hilary S. (LAKEWOOD, OH) - 9/16/2025
I have been using all of the Systeme 41 products for a number of years and at age 81 people tell me I look very good for my age. My husband's niece came to visit us last year (she is in her 60's) and my husband told me I looked much, much better than her!
  I Recommend This Product
  Verified Customer
The best I've used *
By Cindy C. (Grants Pass, OR) - 9/8/2025
I have several jars of different brands of face creams in the cabinet, but none of them perform as well as Systeme-41. I ran out of Systeme-41 and I used the other creams for a couple of months. Wow, I noticed more wrinkles from not using Systeme-41. i was actually shocked at my reflection. I like how this cream doesn't leave a heavy residue that clogs pores.
  I Recommend This Product
  Verified Customer
Systeme 41 day cream *
By Deborah T. (Manassas, VA) - 7/16/2025
I have been using Systeme41 for over 5 years. It has helped my skin stay young and supple. I use the day and night creams and the vitamin C serum. Occasionally I use the eye serum. I tried using another less expensive product ( The Ordinary) just recently for my face but it just couldn’t compare so I am back for good. Systeme41 is an excellent product.
  I Recommend This Product
  Verified Customer
I love System 41 skincare products  *
By Joan M. (Delray Beach, FL) - 6/22/2025
I’ve been using the moisturizers, cleanser, and the microdermabrasion scrub for years. I love the way my skin looks and feels. After using many expensive cremes, these are my favorites. I highly recommend these products.
  I Recommend This Product
  Verified Customer
Excellent products! *
By Paula B. (Stockton, CA) - 7/1/2024
I’ve used System 41 for months now and have seen an overall improvement in my skin. It goes on beautifully and doesn’t pack on a lot of excess creams that make your makeup slide off. I’ve tried lots of products but I keep on going back to System 41 as the best overall skin care products.
  I Recommend This Product
  Verified Customer
* Above are actual reviews from our customers. These customer’s statements may not reflect the typical purchaser’s experience and are not intended to represent or guarantee that anyone will achieve the same or similar results. The reviews should not be taken as the results a typical user will get. Your results may vary.

Ingredients: Night Treatment: aloe vera leaf juice, sunflower seed oil, palmitoyl Hexapeptide-12, shea butter, candelilla/jojoba/rice bran polyglyceryl-3 esters, palmitoyl tripeptide-37, caprooyl tetrapeptide-3, apple fruit cell culture extract, rose hip seed oil, caprylic/capric triglyceride, kukui seed oil, swertia chirata extract, macadamia seed oil, glycerin, coconut oil, glyceryl stearate, neem oil, xylitylglucoside, anhydroxylitol, xylitol, sodium stearoyl lactylate, safflower oleosomes, cetearyl alcohol, hyaluronic acid, red algae extract, pomegranate fruit extract, maltodextrin, chamomile flower extract, calendula flower extract, green tea leaf extract, ceramide ng, gotu kola extract, arnica flower extract, pichia/resveratrol ferment extract, bamboo extract, pea extract, glucosamine HCl, willow bark extract, hydrolyzed algin, chlorella vulgaris extract, bakuchiol extract, sea water, phytosteryl isostearate, phospholipids, biosaccharide gum-1, lecithin, alpha glucan oligosaccharide, tocopherol acetate, retinyl palmitate, ascorbic acid, tetrahexyldecyl ascorbate, niacinamide, pantothenic acid, pyridoxine, cholecalciferol, thioctic acid, citric acid, glyceryl caprylate, glyceryl undecylenate, ubiquinone, dimethylaminoethanol, natural fragrance, xanthan gum, sodium phytate. Day Creme: aloe vera leaf juice, sunflower seed oil, caprylic/capric triglyceride, kukui seed oil, macadamia seed oil, cetearyl olivate, sorbitan olivate, shea butter, safflower oleosomes, hydrogenated olive oil, olive fruit oil, olive oil unsaponifiables, neem oil, glycerin, palmitoyl tripeptide-37, caprooyl tetrapeptide-3, myristlyl myristate, rose hip seed oil, phytosteryl isostearate, cetearyl alcohol, grape fruit cell extract, pomegranate fruit extract, red algae extract, xylitylglucoside, anhydroxylitol, xylitol, chamomile flower extract, calendula flower extract, gotu kola extract, arnica flower extract, ceramide ng, swertia chirata extract, phospholipids, green tea leaf extract, hyaluronic acid, biosaccharide gum-1, alpha-glucan oligosaccharide, oat kernel extract, hydrolyzed algin, chlorella vulgaris extract, sea water, tocopherol acetate, lecithin, retinyl palmitate, ascorbic acid, tetrahexyldecyl ascorbate, niacinamide, pantothenic acid, isomalt, pyridoxine, cholecalciferol, thioctic acid, glyceryl caprylate, glyceryl undecylenate, ubiquinone, dimethylaminoethanol, natural fragrance, sodium phytate, xanthan gum.
* Dr. Janet Zand is compensated by Système 41 for her work in formulating and endorsing this product.

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